| Gene Information | |
|---|---|
| Gene Name | PAR4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 385 |
| Protein Names | Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96RI0 |
| Gene Card | F2RL3 |
| Uniprot ID | Q96RI0 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ZPK (X-ray 1.80A ) 3QDZ (X-ray 2.80A ) |
| DBSNP | rs773902 rs2230799 rs2227346 rs2227376 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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