| Gene Information | |
|---|---|
| Gene Name | PAPSS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 614 |
| Protein Names | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK 2) (SK2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000198682 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O95340 |
| Gene Card | PAPSS2 |
| Uniprot ID | O95340 |
| Pfam | PF01747; PF14306 |
| In ASD | no |
| Allosteric Prediction | yes (0.178452463) |
| Ortholog in Animals | Alpaca_ PAPSS2 ( ortholog_one2one ) GuineaPig_ PAPSS2 ( ortholog_one2one ) Macaque_ PAPSS2 ( ortholog_one2one ) Mouse_ Papss2 ( ortholog_one2one ) Pig_ PAPSS2 ( ortholog_one2one ) Rat_ Papss2 ( ortholog_one2one ) Rabbit_ PAPSS2 ( ortholog_one2one ) |
| Ohnologs | PAPSS1 |
| Paralogs | PAPSS1 |
| Tissue | NA |
| Tissue Specificity | Expressed in cartilage and adrenal gland. {ECO:0000269|PubMed:19474428}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2AX4 (X-ray 2.50A ) 7FH3 (X-ray 1.80A ) 7FHA (X-ray 2.00A ) |
| DBSNP | rs17173698 rs121908951 rs774709274 rs138943074 rs45624631 rs45467596 rs17129133 |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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