| Gene Information | |
|---|---|
| Gene Name | PAPSS |
| Organism | Homo sapiens (Human) |
| Gene Length | 624 |
| Protein Names | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43252 |
| Gene Card | PAPSS1 |
| Uniprot ID | O43252 |
| Pfam | PF01747; PF14306 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver. Also expressed in high endothelial venules (HEV) cells and in cartilage. {ECO:0000269|PubMed:9576487}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X6V (X-ray 1.75A ) 1XJQ (X-ray 2.06A ) 1XNJ (X-ray 1.98A ) 2OFW (X-ray 2.05A ) 2OFX (X-ray 1.90A ) 2PEY (X-ray 1.88A ) 2PEZ (X-ray 1.40A ) 2QJF (X-ray 2.20A ) |
| DBSNP | rs1127008 rs1127014 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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