| Gene Information | |
|---|---|
| Gene Name | PAPOLG |
| Organism | Homo sapiens (Human) |
| Gene Length | 736 |
| Protein Names | Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000115421 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BWT3 |
| Gene Card | PAPOLG |
| Uniprot ID | Q9BWT3 |
| Pfam | PF01909; PF04928; PF04926 |
| In ASD | no |
| Allosteric Prediction | no (-1.480429007) |
| Ortholog in Animals | Alpaca_ PAPOLG ( ortholog_one2one ) Dog_ PAPOLG ( ortholog_one2one ) GuineaPig_ PAPOLG ( ortholog_one2one ) Macaque_ PAPOLG ( ortholog_one2one ) Mouse_ Papolg ( ortholog_one2one ) Pig_ PAPOLG ( ortholog_one2one ) Rat_ Papolg ( ortholog_one2one ) Rabbit_ PAPOLG ( ortholog_one2one ) |
| Ohnologs | PAPOLA |
| Paralogs | PAPOLB, PAPOLA |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in testis, and weakly in other tissues. Overexpressed in several tumors. {ECO:0000269|PubMed:11463842}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 4LT6 (X-ray 2.79A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11287430, ECO:0000269|PubMed:11431479, ECO:0000269|PubMed:11463842}. |
| Mouse PG classification | NA |
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