Gene Information
Gene NameACSS2
OrganismHomo sapiens (Human)
Gene Length701
Protein NamesAcetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acetyl-CoA synthetase 1) (AceCS1) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme) (Propionate--CoA ligase) (EC 6.2.1.17)
Target Nameacetyl-coenzyme a synthetase, cytoplasmic
Target TypeNA
Gene Age950 ( ENSG00000131069 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ9NR19
Gene CardACSS2
Uniprot IDQ9NR19
PfamPF16177; PF00501; PF13193
In ASDno
Allosteric Predictionyes (0.316093666)
Ortholog in AnimalsAlpaca_ ACSS2 ( ortholog_one2one )
Dog_ ACSS2 ( ortholog_one2one )
GuineaPig_ ACSS2 ( ortholog_one2one )
Macaque_ ACSS2 ( ortholog_one2one )
Mouse_ Acss2 ( ortholog_one2one )
Pig_ ACSS2 ( ortholog_one2one )
Rat_ Acss2 ( ortholog_one2one )
Rabbit_ ACSS2 ( ortholog_one2one )
OhnologsNA
ParalogsACSM4, ACSM2B, ACSM2A, AACS, ACSM3, AASDH, ACSS3, ACSM1, ACSM5, ACSM6, ACSF2, ACSF3, ACSS1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:10843999, ECO:0000269|PubMed:28003429}.
Mouse PG classificationNA
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