| Gene Information | |
|---|---|
| Gene Name | PAOX |
| Organism | Homo sapiens (Human) |
| Gene Length | 511 |
| Protein Names | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000148832 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q6QHF9 |
| Gene Card | PAOX |
| Uniprot ID | Q6QHF9 |
| Pfam | PF01593 |
| In ASD | no |
| Allosteric Prediction | yes (0.135525098) |
| Ortholog in Animals | Alpaca_ PAOX ( ortholog_one2one ) Dog_ PAOX ( ortholog_one2one ) GuineaPig_ PAOX ( ortholog_one2one ) Macaque_ PAOX ( ortholog_one2one ) Mouse_ Paox ( ortholog_one2one ) Pig_ PAOX ( ortholog_one2one ) Rat_ Paox ( ortholog_one2one ) Rabbit_ PAOX ( ortholog_one2one ) |
| Ohnologs | SMOX |
| Paralogs | KDM1A, MAOA, SMOX, PPOX, KDM1B, MAOB, IL4I1 |
| Tissue | small.intestine, testis |
| Tissue Specificity | Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. {ECO:0000269|PubMed:12477380}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Peroxisome {ECO:0000250}. Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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