| Gene Information | |
|---|---|
| Gene Name | DCAF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 860 |
| Protein Names | DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000143164 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q58WW2 |
| Gene Card | DCAF6 |
| Uniprot ID | Q58WW2 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.999851441) |
| Ortholog in Animals | Alpaca_ DCAF6 ( ortholog_one2one ) Dog_ DCAF6 ( ortholog_one2one ) GuineaPig_ DCAF6 ( ortholog_one2one ) Macaque_ DCAF6 ( ortholog_one2one ) Mouse_ Dcaf6 ( ortholog_one2one ) Pig_ DCAF6 ( ortholog_one2one ) Rat_ Dcaf6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DCAF8L2, DCAF8L1, DCAF8, WDTC1, DCAF5 |
| Tissue | testis |
| Tissue Specificity | Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland. {ECO:0000269|PubMed:15784617}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3I7O (X-ray 2.80A ) |
| DBSNP | rs11558511 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15784617}. |
| Mouse PG classification | NA |
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