| Gene Information | |
|---|---|
| Gene Name | PANK |
| Organism | Homo sapiens (Human) |
| Gene Length | 598 |
| Protein Names | Pantothenate kinase 1 (hPanK) (hPanK1) (EC 2.7.1.33) (Pantothenic acid kinase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TE04 |
| Gene Card | PANK1 |
| Uniprot ID | Q8TE04 |
| Pfam | PF03630 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. {ECO:0000269|PubMed:11809413, ECO:0000269|PubMed:14523052}.; [Isoform 2]: Detected at much lower levels in kidney, liver, brain and testis and not detected in heart or skeletal muscle. {ECO:0000269|PubMed:14523052}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2I7N (X-ray 1.90A ) 3SMP (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14523052}.; [Isoform 1]: Nucleus {ECO:0000269|PubMed:23152917}. Nucleus, nucleolus {ECO:0000269|PubMed:23152917}.; [Isoform 2]: Cytoplasm, cytosol {ECO:0000269|PubMed:23152917}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:23152917}. Recycling endosome {ECO:0000269|PubMed:23152917}. |
| Mouse PG classification | NA |
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