| Gene Information | |
|---|---|
| Gene Name | TGM5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 720 |
| Protein Names | Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase X) (TG(X)) (TGX) (TGase X) (Transglutaminase-5) (TGase-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000104055 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O43548 |
| Gene Card | TGM5 |
| Uniprot ID | O43548 |
| Pfam | PF00927; PF01841; PF00868 |
| In ASD | no |
| Allosteric Prediction | no (-0.745661736) |
| Ortholog in Animals | Alpaca_ TGM5 ( ortholog_one2one ) Dog_ TGM5 ( ortholog_one2one ) GuineaPig_ TGM5 ( ortholog_one2one ) Macaque_ TGM5 ( ortholog_one2one ) Mouse_ Tgm5 ( ortholog_one2one ) Pig_ TGM5 ( ortholog_one2one ) Rat_ Tgm5 ( ortholog_one2one ) Rabbit_ TGM5 ( ortholog_one2one ) |
| Ohnologs | TGM3, TGM2 |
| Paralogs | TGM7, TGM6, TGM3, EPB42, TGM2, TGM4, TGM1, F13A1 |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Expressed in foreskin keratinocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs757598618 rs113463533 rs112292549 rs28756768 rs7171797 rs35985214 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15290349}. Note=Associated with intermediate filaments. |
| Mouse PG classification | NA |
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