Gene Information
Gene NamePAGA
OrganismHomo sapiens (Human)
Gene Length199
Protein NamesPeroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ06830
Gene CardPRDX1
Uniprot IDQ06830
PfamPF10417; PF00578
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001823(Rat);0.008(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2RII  (X-ray  2.60A  3HY2  (X-ray  2.10A  4XCS  (X-ray  2.10A  7LJ1  (X-ray  2.97A 
DBSNP rs34034070 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:17081065, ECO:0000269|PubMed:9497357}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Mouse PG classificationNA
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