| Gene Information | |
|---|---|
| Gene Name | PAG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 432 |
| Protein Names | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000076641 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NWQ8 |
| Gene Card | PAG1 |
| Uniprot ID | Q9NWQ8 |
| Pfam | PF15347 |
| In ASD | no |
| Allosteric Prediction | no (-0.180525772) |
| Ortholog in Animals | Alpaca_ PAG1 ( ortholog_one2one ) Dog_ PAG1 ( ortholog_one2one ) GuineaPig_ PAG1 ( ortholog_one2one ) Macaque_ PAG1 ( ortholog_one2one ) Mouse_ Pag1 ( ortholog_one2one ) Pig_ PAG1 ( ortholog_one2one ) Rat_ Pag1 ( ortholog_one2one ) Rabbit_ PAG1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Present in germinal center B-cells, plasma cells, T-cells, monocytes and platelets (at protein level). {ECO:0000269|PubMed:10790433, ECO:0000269|PubMed:16160011}. |
| Pharmacological Animal Models | 0.044130(Chimpanzee);0.058983(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10790433, ECO:0000269|PubMed:18070987}; Single-pass type III membrane protein {ECO:0000269|PubMed:10790433, ECO:0000269|PubMed:18070987}. Note=Present in lipid rafts. |
| Mouse PG classification | NA |
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