| Gene Information | |
|---|---|
| Gene Name | PAF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 305 |
| Protein Names | Peroxisome biogenesis factor 2 (EC 2.3.2.27) (EC 2.3.2.36) (35 kDa peroxisomal membrane protein) (Peroxin-2) (Peroxisomal membrane protein 3) (Peroxisome assembly factor 1) (PAF-1) (RING finger protein 72) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000006712 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P28328 |
| Gene Card | PEX2 |
| Uniprot ID | P28328 |
| Pfam | PF04757; PF00097 |
| In ASD | no |
| Allosteric Prediction | yes (0.296014285) |
| Ortholog in Animals | Alpaca_ PAF1 ( ortholog_one2one ) Dog_ PAF1 ( ortholog_one2one ) Macaque_ PAF1 ( ortholog_one2one ) Mouse_ Paf1 ( ortholog_one2one ) Pig_ PAF1 ( ortholog_one2one ) Rat_ Paf1 ( ortholog_one2one ) Rabbit_ PAF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.069463(Mouse);NULL(Rat);0.040000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs61752119 rs10087163 |
| Subcellular location [CC] | Peroxisome membrane {ECO:0000269|PubMed:12751901}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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