| Gene Information | |
|---|---|
| Gene Name | PAF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 531 |
| Protein Names | RNA polymerase II-associated factor 1 homolog (hPAF1) (Pancreatic differentiation protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000006712 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N7H5 |
| Gene Card | PAF1 |
| Uniprot ID | Q8N7H5 |
| Pfam | PF03985 |
| In ASD | no |
| Allosteric Prediction | yes (0.296014285) |
| Ortholog in Animals | Alpaca_ PAF1 ( ortholog_one2one ) Dog_ PAF1 ( ortholog_one2one ) Macaque_ PAF1 ( ortholog_one2one ) Mouse_ Paf1 ( ortholog_one2one ) Pig_ PAF1 ( ortholog_one2one ) Rat_ Paf1 ( ortholog_one2one ) Rabbit_ PAF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.013820(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4M6T (X-ray 2.50A ) 5ZYQ (X-ray 2.53A ) 6GMH (EM 3.10A ) 6TED (EM 3.10A ) 7OOP (EM 2.90A ) 7OPC (EM 3.00A ) 7OPD (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16491129, ECO:0000269|PubMed:30367041}. Note=Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin. |
| Mouse PG classification | NA |
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