| Gene Information | |
|---|---|
| Gene Name | RASGEF1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 481 |
| Protein Names | Ras-GEF domain-containing family member 1A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000198915 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N9B8 |
| Gene Card | RASGEF1A |
| Uniprot ID | Q8N9B8 |
| Pfam | PF00617; PF00618 |
| In ASD | no |
| Allosteric Prediction | no (-0.751661356) |
| Ortholog in Animals | Alpaca_ RASGEF1A ( ortholog_one2one ) Dog_ RASGEF1A ( ortholog_one2one ) GuineaPig_ RASGEF1A ( ortholog_one2one ) Macaque_ RASGEF1A ( ortholog_one2one ) Mouse_ Rasgef1a ( ortholog_one2one ) Pig_ RASGEF1A ( ortholog_one2one ) Rat_ Rasgef1a ( ortholog_one2one ) |
| Ohnologs | RASGEF1B, RASGEF1C |
| Paralogs | RALGDS, RASGRF2, RASGRP3, SOS2, RAPGEF3, RAPGEF6, RASGRF1, RAPGEF2, RGL1, RAPGEF1, RASGEF1B, RASGRP2, RGL2, SOS1, RGL3, RALGPS1, RALGPS2, RAPGEF4, RGL4, RASGRP4, RAPGEFL1, RAPGEF5, RASGRP1, RASGEF1C |
| Tissue | NA |
| Tissue Specificity | Detected in brain and spinal cord. Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies. {ECO:0000269|PubMed:17121879}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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