| Gene Information | |
|---|---|
| Gene Name | MAPK13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 365 |
| Protein Names | Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4) |
| Target Name | mitogen-activated protein kinases |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000156711 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O15264 |
| Gene Card | MAPK13 |
| Uniprot ID | O15264 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (1.299367344) |
| Ortholog in Animals | Alpaca_ MAPK13 ( ortholog_one2one ) Dog_ MAPK13 ( ortholog_one2one ) GuineaPig_ MAPK13 ( ortholog_one2one ) Macaque_ MAPK13 ( ortholog_one2one ) Mouse_ Mapk13 ( ortholog_one2one ) Pig_ MAPK13 ( ortholog_one2one ) Rat_ Mapk13 ( ortholog_one2one ) Rabbit_ MAPK13 ( ortholog_one2one ) |
| Ohnologs | MAPK11, MAPK12 |
| Paralogs | MAPK8, MAPK10, MAPK1, MAPK6, MAPK12, SRPK1, SRPK3, MAPK4, NLK, MAPK14, MAPK3, MOK, MAPK11, MAK, MAPK15, MAPK7, SRPK2, MAPK9, CILK1 |
| Tissue | NA |
| Tissue Specificity | Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells. {ECO:0000269|PubMed:10201954, ECO:0000269|PubMed:9374491}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3COI (X-ray 2.09A ) 4EYJ (X-ray 2.10A ) 4EYM (X-ray 2.35A ) 4MYG (X-ray 2.59A ) 4YNO (X-ray 1.70A ) 5EKN (X-ray 2.59A ) 5EKO (X-ray 2.00A ) |
| DBSNP | rs55776345 rs55990045 rs41270090 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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