| Gene Information | |
|---|---|
| Gene Name | ZIC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 532 |
| Protein Names | Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000043355 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95409 |
| Gene Card | ZIC2 |
| Uniprot ID | O95409 |
| Pfam | PF00096; PF18366 |
| In ASD | no |
| Allosteric Prediction | no (-0.955528618) |
| Ortholog in Animals | Alpaca_ ZIC2 ( ortholog_one2one ) Dog_ ZIC2 ( ortholog_one2one ) GuineaPig_ ZIC2 ( ortholog_one2one ) Macaque_ ZIC2 ( ortholog_one2one ) Mouse_ Zic2 ( ortholog_one2one ) Pig_ ZIC2 ( ortholog_one2one ) Rat_ Zic2 ( ortholog_one2one ) |
| Ohnologs | ZIC3, ZIC1, ZIC4 |
| Paralogs | AEBP2, GLIS3, GLI2, ZXDC, GLIS2, GLIS1, ZXDA, ZXDB, ZIC4, ZIC5, ZIC3, GLI1, GLI3, ZIC1 |
| Tissue | cerebellum, brain, cerebellar.hemisphere |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1185333947 rs1325393230 rs1594291868 rs794729641 |
| Subcellular location [CC] | Nucleus. Cytoplasm {ECO:0000250}. Note=Localizes in the cytoplasm in presence of MDFIC overexpression. Both phosphorylated and unphosphorylated forms are localized in the nucleus (By similarity). {ECO:0000250}. |
| Mouse PG classification | HPG |
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