| Gene Information | |
|---|---|
| Gene Name | P5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 440 |
| Protein Names | Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15084 |
| Gene Card | PDIA6 |
| Uniprot ID | Q15084 |
| Pfam | PF00085 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in platelets (at protein level). {ECO:0000269|PubMed:15466936}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X5D (NMR - ) 3VWW (X-ray 1.93A ) 3W8J (X-ray 2.10A ) 4EF0 (X-ray 1.50A ) 4GWR (X-ray 1.81A ) |
| DBSNP | rs4807 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000269|PubMed:15466936}. Cell membrane {ECO:0000269|PubMed:15466936}. Melanosome {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). {ECO:0000269|PubMed:12643545}. |
| Mouse PG classification | NA |
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