| Gene Information | |
|---|---|
| Gene Name | P450RAI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 497 |
| Protein Names | Cytochrome P450 26A1 (EC 1.14.13.-) (Cytochrome P450 retinoic acid-inactivating 1) (Cytochrome P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) (Retinoic acid-metabolizing cytochrome) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43174 |
| Gene Card | CYP26A1 |
| Uniprot ID | O43174 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in most fetal and adult tissues with highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain (PubMed:9826557). Expressed at high levels in lung, pancreas, skin and uterus (at protein level) (PubMed:22020119). Lower expression level is detected in spleen, kidney, intestine and adipose tissue (at protein level) (PubMed:22020119). {ECO:0000269|PubMed:22020119, ECO:0000269|PubMed:9826557}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000305|PubMed:9716180}; Peripheral membrane protein. Microsome membrane {ECO:0000269|PubMed:9716180}; Peripheral membrane protein. |
| Mouse PG classification | NA |
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