| Gene Information | |
|---|---|
| Gene Name | P3H1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 736 |
| Protein Names | Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1) |
| Target Name | prolyl 3-hydroxylase 1 |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000117385 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q32P28 |
| Gene Card | P3H1 |
| Uniprot ID | Q32P28 |
| Pfam | PF13640 |
| In ASD | no |
| Allosteric Prediction | no (-0.099314432) |
| Ortholog in Animals | Alpaca_ P3H1 ( ortholog_one2one ) Dog_ P3H1 ( ortholog_one2one ) GuineaPig_ P3H1 ( ortholog_one2one ) Macaque_ P3H1 ( ortholog_one2one ) Mouse_ P3h1 ( ortholog_one2one ) Pig_ P3H1 ( ortholog_one2one ) Rat_ P3h1 ( ortholog_one2one ) Rabbit_ P3H1 ( ortholog_one2one ) |
| Ohnologs | P3H2, P3H3, CRTAP |
| Paralogs | P3H3, P3H2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6700677 rs3738501 rs11581921 rs3738497 |
| Subcellular location [CC] | [Isoform 1]: Endoplasmic reticulum.; Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG). {ECO:0000269|PubMed:19088120}. |
| Mouse PG classification | HPG |
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