| Gene Information | |
|---|---|
| Gene Name | DEDD |
| Organism | Homo sapiens (Human) |
| Gene Length | 318 |
| Protein Names | Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000158796 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75618 |
| Gene Card | DEDD |
| Uniprot ID | O75618 |
| Pfam | PF01335 |
| In ASD | no |
| Allosteric Prediction | no (-0.803325265) |
| Ortholog in Animals | Alpaca_ DEDD ( ortholog_one2one ) Dog_ DEDD ( ortholog_one2one ) GuineaPig_ DEDD ( ortholog_one2one ) Macaque_ DEDD ( ortholog_one2one ) Mouse_ Dedd ( ortholog_one2one ) Pig_ DEDD ( ortholog_one2one ) Rat_ Dedd ( ortholog_one2one ) Rabbit_ DEDD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DEDD2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in testis. {ECO:0000269|PubMed:9832420}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus, nucleolus {ECO:0000250}. Note=Translocated to the nucleus during CD95-mediated apoptosis where it is localized in the nucleoli (By similarity). Following apoptosis induction, the mono and/or diubiquitination form increases and forms filamentous structures that colocalize with KRT8 and KRT18 intermediate filament network in simple epithelial cells. {ECO:0000250}. |
| Mouse PG classification | NA |
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