| Gene Information | |
|---|---|
| Gene Name | FAM83D |
| Organism | Homo sapiens (Human) |
| Gene Length | 585 |
| Protein Names | Protein FAM83D (Spindle protein CHICA) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000101447 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H4H8 |
| Gene Card | FAM83D |
| Uniprot ID | Q9H4H8 |
| Pfam | PF07894 |
| In ASD | no |
| Allosteric Prediction | no (-0.445908018) |
| Ortholog in Animals | Alpaca_ FAM83D ( ortholog_one2one ) Dog_ FAM83D ( ortholog_one2one ) GuineaPig_ FAM83D ( ortholog_one2one ) Mouse_ Fam83d ( ortholog_one2one ) Pig_ FAM83D ( ortholog_one2one ) Rat_ Fam83d ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FAM83A, FAM83B, FAM83F, FAM83G, FAM83H, FAM83C, FAM83E |
| Tissue | brain, sigmoid.colon |
| Tissue Specificity | Expressed in the testis. {ECO:0000269|PubMed:22965910}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5E0L (X-ray 1.31A ) 5E0M (X-ray 1.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18445686}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18445686}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:15561729, ECO:0000269|PubMed:18485706}. Note=Primarily cytoplasmic during interphase, but at prophase, associates with spindle microtubules, with a clear concentration toward the spindle poles. It persists on spindle microtubules through metaphase and anaphase. {ECO:0000269|PubMed:18485706}. |
| Mouse PG classification | NA |
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