| Gene Information | |
|---|---|
| Gene Name | P2RY13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | P2Y purinoceptor 13 (P2Y13) (G-protein coupled receptor 86) (G-protein coupled receptor 94) |
| Target Name | p2y purinoceptor 13 |
| Target Type | Literature-reported target |
| Gene Age | 544 ( ENSG00000181631 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BPV8 |
| Gene Card | P2RY13 |
| Uniprot ID | Q9BPV8 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.988579044) |
| Ortholog in Animals | Alpaca_ P2RY13 ( ortholog_one2one ) GuineaPig_ P2RY13 ( ortholog_one2one ) Macaque_ P2RY13 ( ortholog_one2one ) Mouse_ P2ry13 ( ortholog_one2one ) Pig_ P2RY13 ( ortholog_one2one ) Rat_ P2ry13 ( ortholog_one2one ) Rabbit_ P2RY13 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR34, GPR171, PTAFR, P2RY12, GPR87, P2RY14 |
| Tissue | lung, spleen, whole.blood |
| Tissue Specificity | Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1466684 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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