| Gene Information | |
|---|---|
| Gene Name | TMEM126A |
| Organism | Homo sapiens (Human) |
| Gene Length | 195 |
| Protein Names | Transmembrane protein 126A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000171202 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H061 |
| Gene Card | TMEM126A |
| Uniprot ID | Q9H061 |
| Pfam | PF07114 |
| In ASD | no |
| Allosteric Prediction | no (-1.46682977) |
| Ortholog in Animals | Alpaca_ TMEM126A ( ortholog_one2one ) Dog_ TMEM126A ( ortholog_one2one ) GuineaPig_ TMEM126A ( ortholog_one2one ) Macaque_ TMEM126A ( ortholog_one2one ) Mouse_ Tmem126a ( ortholog_one2one ) Pig_ TMEM126A ( ortholog_one2one ) Rat_ Tmem126a ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TMEM126B |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in brain, cerebellum, skeletal muscle, testis. High expression also found in fetal brain, fetal retinal pigmentary epithelium, and fetal retina. Highly expressed in retinal ganglion cells. {ECO:0000269|PubMed:19327736, ECO:0000269|PubMed:23500070}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11556797 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:19327736, ECO:0000269|PubMed:23500070}; Multi-pass membrane protein {ECO:0000269|PubMed:19327736, ECO:0000269|PubMed:23500070}. |
| Mouse PG classification | NA |
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