| Gene Information | |
|---|---|
| Gene Name | OXTR |
| Organism | Homo sapiens (Human) |
| Gene Length | 389 |
| Protein Names | Oxytocin receptor (OT-R) |
| Target Name | oxytocin receptor |
| Target Type | Successful target |
| Gene Age | 645 ( ENSG00000180914 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P30559 |
| Gene Card | OXTR |
| Uniprot ID | P30559 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.452173416) |
| Ortholog in Animals | Alpaca_ OXTR ( ortholog_one2one ) Dog_ OXTR ( ortholog_one2one ) GuineaPig_ OXTR ( ortholog_one2one ) Macaque_ OXTR ( ortholog_one2one ) Mouse_ Oxtr ( ortholog_one2one ) Pig_ OXTR ( ortholog_one2one ) Rat_ Oxtr ( ortholog_one2one ) |
| Ohnologs | AVPR2, AVPR1A, AVPR1B |
| Paralogs | QRFPR, NPFFR1, HCRTR2, HCRTR1, NPFFR2, CCKBR, CCKAR, GNRHR, GALR3, GPR22, GPR150, FFAR4, GALR1, AVPR2, AVPR1A, AVPR1B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6TPK (X-ray 3.20A ) 7QVM (EM 3.25A ) 7RYC (EM 2.90A ) |
| DBSNP | rs237906 rs4686302 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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