| Gene Information | |
|---|---|
| Gene Name | OXSR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 527 |
| Protein Names | Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) |
| Target Name | serine/threonine-protein kinase osr1 |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000172939 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O95747 |
| Gene Card | OXSR1 |
| Uniprot ID | O95747 |
| Pfam | PF12202; PF00069 |
| In ASD | yes |
| Allosteric Prediction | yes (0.731598906) |
| Ortholog in Animals | Alpaca_ OXSR1 ( ortholog_one2one ) Dog_ OXSR1 ( ortholog_one2one ) GuineaPig_ OXSR1 ( ortholog_one2one ) Macaque_ OXSR1 ( ortholog_one2one ) Mouse_ Oxsr1 ( ortholog_one2one ) |
| Ohnologs | STK39 |
| Paralogs | PAK5, PAK6, PAK4, SBK2, STK39, MAP4K1, PAK2, PAK1, PAK3, MINK1, TNIK, MAP4K5, SLK, MAP3K14, MAP3K19, STRADB, STK4, MAP3K1, TAOK2, MAP4K3, NRK, STRADA, MAP2K3, STK10, MAP2K6, STK26, TAOK3, TAOK1, MAP3K8, MAP4K2, STK3, NEK4, STK25, STK24, MAP4K4 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in all tissue examined. {ECO:0000269|PubMed:10083736}. |
| Pharmacological Animal Models | 0.017047(Chimpanzee);0.078428(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2V3S (X-ray 1.70A ) 2VWI (X-ray 2.15A ) 3DAK (X-ray 2.25A ) 7OKW (X-ray 1.62A ) |
| DBSNP | rs6599079 rs35295772 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22361696}. |
| Mouse PG classification | NA |
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