| Gene Information | |
|---|---|
| Gene Name | OXSM |
| Organism | Homo sapiens (Human) |
| Gene Length | 459 |
| Protein Names | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (EC 2.3.1.41) (Beta-ketoacyl-ACP synthase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000151093 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NWU1 |
| Gene Card | OXSM |
| Uniprot ID | Q9NWU1 |
| Pfam | PF00109; PF02801 |
| In ASD | no |
| Allosteric Prediction | no (-0.934934246) |
| Ortholog in Animals | Alpaca_ OXSM ( ortholog_one2one ) Dog_ OXSM ( ortholog_one2one ) GuineaPig_ OXSM ( ortholog_one2one ) Macaque_ OXSM ( ortholog_one2one ) Mouse_ Oxsm ( ortholog_one2one ) Pig_ OXSM ( ortholog_one2one ) Rat_ Oxsm ( ortholog_one2one ) Rabbit_ OXSM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FASN |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Higher expression in heart, skeletal muscle, liver and kidney which contain high levels of active mitochondria. {ECO:0000269|PubMed:15668256}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2C9H (X-ray 1.80A ) 2IWY (X-ray 2.06A ) 2IWZ (X-ray 1.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:15668256}. |
| Mouse PG classification | NA |
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