| Gene Information | |
|---|---|
| Gene Name | IL13RA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 427 |
| Protein Names | Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000131724 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P78552 |
| Gene Card | IL13RA1 |
| Uniprot ID | P78552 |
| Pfam | PF18001; PF09240 |
| In ASD | no |
| Allosteric Prediction | no (-0.536679056) |
| Ortholog in Animals | Alpaca_ IL13RA1 ( ortholog_one2one ) Dog_ IL13RA1 ( ortholog_one2one ) GuineaPig_ IL13RA1 ( ortholog_one2one ) Macaque_ IL13RA1 ( ortholog_one2one ) Mouse_ Il13ra1 ( ortholog_one2one ) Pig_ IL13RA1 ( ortholog_one2one ) Rat_ Il13ra1 ( ortholog_one2many ) Rabbit_ IL13RA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRLF1, IL13RA2, IL11RA, CNTFR, IL2RG, CRLF2, IL31RA, IL3RA, IL6ST, IL12RB1, CSF3R, IL12RB2, GHR, CSF2RA, IL6R, IL27RA, IL23R, LIFR, OSMR, IL5RA, EBI3, PRLR, LEPR |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);0.200000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3BPN (X-ray 3.02A ) 3BPO (X-ray 3.00A ) 4HWB (X-ray 2.61A ) 5E4E (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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