| Gene Information | |
|---|---|
| Gene Name | OTX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Homeobox protein OTX1 (Orthodenticle homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000115507 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P32242 |
| Gene Card | OTX1 |
| Uniprot ID | P32242 |
| Pfam | PF00046; PF03529 |
| In ASD | no |
| Allosteric Prediction | no (-1.023106938) |
| Ortholog in Animals | Alpaca_ OTX1 ( ortholog_one2one ) Dog_ OTX1 ( ortholog_one2one ) GuineaPig_ OTX1 ( ortholog_one2one ) Macaque_ OTX1 ( ortholog_one2one ) Mouse_ Otx1 ( ortholog_one2one ) Pig_ OTX1 ( ortholog_one2one ) Rat_ Otx1 ( ortholog_one2one ) Rabbit_ OTX1 ( ortholog_one2one ) |
| Ohnologs | CRX, OTX2 |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level). {ECO:0000269|PubMed:19414065}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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