| Gene Information | |
|---|---|
| Gene Name | OTUD5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 571 |
| Protein Names | OTU domain-containing protein 5 (EC 3.4.19.12) (Deubiquitinating enzyme A) (DUBA) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000068308 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96G74 |
| Gene Card | OTUD5 |
| Uniprot ID | Q96G74 |
| Pfam | PF02338 |
| In ASD | no |
| Allosteric Prediction | no (-0.416551117) |
| Ortholog in Animals | Alpaca_ OTUD5 ( ortholog_one2one ) Dog_ OTUD5 ( ortholog_one2one ) GuineaPig_ OTUD5 ( ortholog_one2one ) Macaque_ OTUD5 ( ortholog_one2one ) Mouse_ Otud5 ( ortholog_one2one ) Pig_ OTUD5 ( ortholog_one2one ) Rat_ Otud5 ( ortholog_one2one ) Rabbit_ OTUD5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | OTUD6B, OTUD6A, OTUD3, OTUD1, OTUD4 |
| Tissue | NA |
| Tissue Specificity | Expressed in various tissues, including the liver and placenta, as well as in peripheral blood leukocytes. {ECO:0000269|PubMed:17991829}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3PFY (X-ray 1.70A ) 3TMO (X-ray 2.20A ) 3TMP (X-ray 1.91A ) |
| DBSNP | rs2063805506 rs2063801903 rs2063659512 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:33523931}. |
| Mouse PG classification | NA |
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