| Gene Information | |
|---|---|
| Gene Name | HTR3C |
| Organism | Homo sapiens (Human) |
| Gene Length | 447 |
| Protein Names | 5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C) |
| Target Name | 5-hydroxytryptamine receptor 3c |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000178084 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WXA8 |
| Gene Card | HTR3C |
| Uniprot ID | Q8WXA8 |
| Pfam | PF02931; PF02932 |
| In ASD | no |
| Allosteric Prediction | no (-0.033822275) |
| Ortholog in Animals | Alpaca_ HTR3C ( ortholog_one2one ) Macaque_ HTR3C ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB, HTR3D |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues including adult brain, colon, intestine, lung, muscle and stomach as well as fetal colon and kidney. {ECO:0000269|PubMed:12801637}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs142791028 rs6766410 rs6807362 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17392525}; Multi-pass membrane protein {ECO:0000269|PubMed:17392525}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. |
| Mouse PG classification | NA |
| click here to return to the previous page | |