| Gene Information | |
|---|---|
| Gene Name | OTUB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 234 |
| Protein Names | Ubiquitin thioesterase OTUB2 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Otubain-2) (Ubiquitin-specific-processing protease OTUB2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000089723 ) 3 ( ENSG00000277276 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96DC9 |
| Gene Card | OTUB2 |
| Uniprot ID | Q96DC9 |
| Pfam | PF10275 |
| In ASD | no |
| Allosteric Prediction | no (-1.102886723) |
| Ortholog in Animals | Alpaca_ OTUB2 ( ortholog_one2one ) Dog_ OTUB2 ( ortholog_one2one ) GuineaPig_ OTUB2 ( ortholog_one2one ) Macaque_ OTUB2 ( ortholog_one2one ) Mouse_ Otub2 ( ortholog_one2one ) Pig_ OTUB2 ( ortholog_one2one ) Rat_ Otub2 ( ortholog_one2one ) Rabbit_ OTUB2 ( ortholog_one2one ) |
| Ohnologs | OTUB1 |
| Paralogs | OTUB1 |
| Tissue | testis |
| Tissue Specificity | Widely expressed. Expressed at higher level in brain. {ECO:0000269|PubMed:12704427}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TFF (X-ray 2.10A ) 4FJV (X-ray 2.05A ) 5QIO (X-ray 1.46A ) 5QIP (X-ray 1.63A ) 5QIQ (X-ray 1.44A ) 5QIR (X-ray 1.43A ) 5QIS (X-ray 1.53A ) 5QIT (X-ray 1.46A ) 5QIU (X-ray 1.56A ) 5QIV (X-ray 1.39A ) 5QIW (X-ray 1.71A ) 5QIX (X-ray 1.39A ) 5QIY (X-ray 1.58A ) 5QIZ (X-ray 1.63A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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