| Gene Information | |
|---|---|
| Gene Name | ALOXE3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 711 |
| Protein Names | Hydroperoxide isomerase ALOXE3 (Epidermis-type lipoxygenase 3) (Epidermal LOX-3) (e-LOX-3) (eLOX-3) (Hydroperoxy dehydratase ALOXE3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Hydroperoxy icosatetraenoate isomerase) (EC 5.4.4.7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000179148 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BYJ1 |
| Gene Card | ALOXE3 |
| Uniprot ID | Q9BYJ1 |
| Pfam | PF00305; PF01477 |
| In ASD | no |
| Allosteric Prediction | no (-0.818630157) |
| Ortholog in Animals | Alpaca_ ALOXE3 ( ortholog_one2one ) Dog_ ALOXE3 ( ortholog_one2one ) GuineaPig_ ALOXE3 ( ortholog_one2one ) Macaque_ ALOXE3 ( ortholog_one2one ) Mouse_ Aloxe3 ( ortholog_one2one ) Pig_ ALOXE3 ( ortholog_one2one ) Rat_ Aloxe3 ( ortholog_one2one ) Rabbit_ ALOXE3 ( ortholog_one2one ) |
| Ohnologs | ALOX15 |
| Paralogs | ALOX12, ALOX15, ALOX5, ALOX15B, ALOX12B |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Predominantly expressed in skin. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 6VB2 (X-ray 1.41A ) |
| DBSNP | rs121434235 rs786205120 rs121434234 rs1355284797 rs121434232 rs147149459 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00726}. |
| Mouse PG classification | HPG |
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