Gene Information
Gene NameOTP
OrganismHomo sapiens (Human)
Gene Length325
Protein NamesHomeobox protein orthopedia
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000171540 )
Evolutionary StageEumetazoa
AlphaFoldDBQ5XKR4
Gene CardOTP
Uniprot IDQ5XKR4
PfamPF00046; PF03826
In ASDno
Allosteric Predictionno (-0.807540606)
Ortholog in AnimalsAlpaca_ OTP ( ortholog_one2one )
Dog_ OTP ( ortholog_one2one )
GuineaPig_ OTP ( ortholog_one2one )
Macaque_ OTP ( ortholog_one2one )
Mouse_ Otp ( ortholog_one2one )
Pig_ OTP ( ortholog_one2one )
Rat_ Otp ( ortholog_one2one )
OhnologsNA
ParalogsARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138, ECO:0000269|PubMed:10458915}.
Mouse PG classificationNA
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