| Gene Information | |
|---|---|
| Gene Name | WDR66 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1149 |
| Protein Names | Cilia- and flagella-associated protein 251 (WD repeat-containing protein 66) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TBY9 |
| Gene Card | CFAP251 |
| Uniprot ID | Q8TBY9 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is highly expressed in testis and, at lower levels, in lung. Very low levels are detected in kidney and brain (PubMed:30122540). In testis, expressed in spermatozoa (at protein level) (PubMed:30122540, PubMed:30122541). Isoform 2 is not detected in testis, lung, kidney, nor in brain (PubMed:30122540). {ECO:0000269|PubMed:30122540, ECO:0000269|PubMed:30122541}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12824001 rs12824001 rs199671406 rs34768683 rs11043265 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A8IRK7}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:30122540, ECO:0000269|PubMed:30122541}. |
| Mouse PG classification | NA |
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