| Gene Information | |
|---|---|
| Gene Name | OSTN |
| Organism | Homo sapiens (Human) |
| Gene Length | 133 |
| Protein Names | Osteocrin (Musclin) [Cleaved into: Processed Osteocrin] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000188729 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P61366 |
| Gene Card | OSTN |
| Uniprot ID | P61366 |
| Pfam | PF11037 |
| In ASD | no |
| Allosteric Prediction | no (-0.787979027) |
| Ortholog in Animals | Alpaca_ OSTN ( ortholog_one2one ) Dog_ OSTN ( ortholog_one2one ) GuineaPig_ OSTN ( ortholog_one2one ) Macaque_ OSTN ( ortholog_one2one ) Mouse_ Ostn ( ortholog_one2one ) Pig_ OSTN ( ortholog_one2one ) Rat_ Ostn ( ortholog_one2one ) Rabbit_ OSTN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | penis |
| Tissue Specificity | Enriched in neocortical regions of the developing cerebral cortex (PubMed:27830782). Not expressed in other compartments of the neocortical wall or in brain regions such as the hippocampus, striatum, mediodorsal nucleus of the thalamus and cerebellum (PubMed:27830782). Also expressed in bone (PubMed:14523025). In developing neonatal rib bone, present at high level in osteoblasts on bone-forming surfaces, in newly incorporated osteocytes and in some late hypertrophic chondrocytes (at protein level) (PubMed:15923362). In adult bone, localizes specifically to osteoblasts and young osteocytes at bone-forming sites (at protein level) (PubMed:15923362). {ECO:0000269|PubMed:14523025, ECO:0000269|PubMed:15923362, ECO:0000269|PubMed:27830782}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:14523025}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |