| Gene Information | |
|---|---|
| Gene Name | IGFR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 374 |
| Protein Names | High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P12314 |
| Gene Card | FCGR1A |
| Uniprot ID | P12314 |
| Pfam | PF00047; PF13895 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Monocyte/macrophage specific. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3RJD (X-ray 2.65A ) 4W4O (X-ray 1.80A ) 4X4M (X-ray 3.48A ) 4ZNE (X-ray 2.42A ) |
| DBSNP | rs619322 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12756162, ECO:0000269|PubMed:8611682}; Single-pass type I membrane protein {ECO:0000269|PubMed:12756162, ECO:0000269|PubMed:8611682}. Note=Stabilized at the cell membrane through interaction with FCER1G. |
| Mouse PG classification | NA |
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