Gene Information
Gene NameOSTA
OrganismHomo sapiens (Human)
Gene Length340
Protein NamesOrganic solute transporter subunit alpha (OST-alpha) (Solute carrier family 51 subunit alpha)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ86UW1
Gene CardSLC51A
Uniprot IDQ86UW1
PfamPF03619
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland;
and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat. {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs939885 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:16317684};
Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250};
Multi-pass membrane protein {ECO:0000250}. Note=Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B (By similarity). Mainly restricted to the lateral and basal membranes of ileal enterocytes. {ECO:0000250}.
Mouse PG classificationNA
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