Gene Information
Gene NameOST
OrganismHomo sapiens (Human)
Gene Length1137
Protein NamesGuanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO15068
Gene CardMCF2L
Uniprot IDO15068
PfamPF13716; PF00169; PF00621; PF07653; PF00435
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC][Isoform 5]: Cytoplasm {ECO:0000269|PubMed:15157669}. Cell membrane {ECO:0000269|PubMed:15157669};
Peripheral membrane protein {ECO:0000269|PubMed:15157669};
Cytoplasmic side {ECO:0000269|PubMed:15157669}.;
[Isoform 3]: Cytoplasm {ECO:0000269|PubMed:15157669}. Endomembrane system {ECO:0000269|PubMed:15157669}. Note=Interaction with membranes enriched in phosphoinositides is mediated by the CRAL-TRIO domain. {ECO:0000269|PubMed:15157669}.;
Cytoplasm {ECO:0000250|UniProtKB:Q64096}. Cell membrane {ECO:0000250|UniProtKB:Q64096};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q64096};
Cytoplasmic side {ECO:0000250|UniProtKB:Q64096}.
Mouse PG classificationNA
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