| Gene Information | |
|---|---|
| Gene Name | OSF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 521 |
| Protein Names | Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13950 |
| Gene Card | RUNX2 |
| Uniprot ID | Q13950 |
| Pfam | PF00853; PF08504 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in osteoblasts. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);0.014286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6VG8 (X-ray 4.31A ) 6VGD (X-ray 4.20A ) 6VGE (X-ray 4.25A ) 6VGG (X-ray 4.31A ) |
| DBSNP | rs104893995 rs104893995 rs104893989 rs201647225 rs1057521068 rs104893990 rs104893993 rs752933596 rs104893991 rs104893992 rs11498198 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:28505335, ECO:0000269|PubMed:28738062}. |
| Mouse PG classification | NA |
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