| Gene Information | |
|---|---|
| Gene Name | OSCAR |
| Organism | Homo sapiens (Human) |
| Gene Length | 282 |
| Protein Names | Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (hOSCAR) (Polymeric immunoglobulin receptor 3) (PIgR-3) (PIgR3) (Poly-Ig receptor 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000170909 ) 3 ( ENSG00000273511 ) 3 ( ENSG00000274703 ) 3 ( ENSG00000275551 ) 3 ( ENSG00000275644 ) 3 ( ENSG00000275736 ) 3 ( ENSG00000276982 ) 3 ( ENSG00000277088 ) 3 ( ENSG00000278378 ) 3 ( ENSG00000278533 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IYS5 |
| Gene Card | OSCAR |
| Uniprot ID | Q8IYS5 |
| Pfam | PF13895 |
| In ASD | no |
| Allosteric Prediction | no (-0.193169314) |
| Ortholog in Animals | Dog_ OSCAR ( ortholog_one2one ) Macaque_ OSCAR ( ortholog_one2one ) Mouse_ Oscar ( ortholog_one2one ) Pig_ OSCAR ( ortholog_one2one ) Rat_ Oscar ( ortholog_one2one ) Rabbit_ OSCAR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IGSF1, TARM1, VSTM1, LAIR2, A1BG, KIR2DL3, KIR3DL3, GP6, KIR3DL2, LILRB2, KIR3DL1, KIR2DS4, LILRB5, KIR2DL4, LILRA2, LILRA4, LILRA6, LILRA5, NCR1, LILRB4, LILRB1, FCAR, LILRA1, LILRB3, KIR2DL1 |
| Tissue | bone.marrow, lung, adipose.tissue, adrenal.gland, heart, kidney, liver, ovary, pancreas, sigmoid.colon, spleen, testis, whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5CJ8 (X-ray 2.02A ) 5CJB (X-ray 2.40A ) 5EIQ (X-ray 2.01A ) 5EIV (X-ray 2.41A ) |
| DBSNP | rs1657535 rs8106130 |
| Subcellular location [CC] | [Isoform 1]: Secreted {ECO:0000305}.; [Isoform 2]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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