| Gene Information | |
|---|---|
| Gene Name | OSBPL5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 879 |
| Protein Names | Oxysterol-binding protein-related protein 5 (ORP-5) (OSBP-related protein 5) (Oxysterol-binding protein homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000021762 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H0X9 |
| Gene Card | OSBPL5 |
| Uniprot ID | Q9H0X9 |
| Pfam | PF01237; PF00169 |
| In ASD | no |
| Allosteric Prediction | no (-0.203790221) |
| Ortholog in Animals | Alpaca_ OSBPL5 ( ortholog_one2one ) Dog_ OSBPL5 ( ortholog_one2one ) GuineaPig_ OSBPL5 ( ortholog_one2one ) Macaque_ OSBPL5 ( ortholog_one2one ) Mouse_ Osbpl5 ( ortholog_one2one ) Pig_ OSBPL5 ( ortholog_one2one ) Rat_ Osbpl5 ( ortholog_one2one ) |
| Ohnologs | OSBPL8 |
| Paralogs | OSBPL10, OSBPL2, OSBP2, OSBPL1A, OSBP, OSBPL8, OSBPL3, OSBPL9, OSBPL11, OSBPL6, OSBPL7 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12504849, ECO:0000269|PubMed:21220512}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6578323 rs2277301 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21220512, ECO:0000269|PubMed:26206935}; Single-pass membrane protein {ECO:0000269|PubMed:21220512}. Note=Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS). Localizes to the cortical endoplasmic reticulum at the EPCS. {ECO:0000269|PubMed:26206935, ECO:0000269|PubMed:30220461}. |
| Mouse PG classification | NA |
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