Gene Information
Gene NameMPHOSPH10
OrganismHomo sapiens (Human)
Gene Length681
Protein NamesU3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000124383 )
Evolutionary StageEukaryota
AlphaFoldDBO00566
Gene CardMPHOSPH10
Uniprot IDO00566
PfamPF04006
In ASDno
Allosteric Predictionno (-1.172182969)
Ortholog in AnimalsAlpaca_ MPHOSPH10 ( ortholog_one2one )
GuineaPig_ MPHOSPH10 ( ortholog_one2one )
Macaque_ MPHOSPH10 ( ortholog_one2one )
Mouse_ Mphosph10 ( ortholog_one2one )
Pig_ MPHOSPH10 ( ortholog_one2one )
Rat_ Mphosph10 ( ortholog_one2one )
Rabbit_ MPHOSPH10 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.453553(Rat);0.093135(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7MQ8  (EM  3.60A  7MQ9  (EM  3.87A  7MQA  (EM  2.70A 
DBSNP rs10199088  rs13010513  rs10175940  rs1813160  rs3732240  rs6574  rs4852764 
Subcellular location [CC]Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:12655004, ECO:0000269|PubMed:9450966}. Chromosome {ECO:0000269|PubMed:9450966}. Note=Fibrillar region of the nucleolus (PubMed:9450966). After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase (PubMed:9450966). In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin (PubMed:9450966). The reassociation with nucleolus is preceeded by the arrival of fibrillarin (PubMed:9450966). {ECO:0000269|PubMed:9450966}.
Mouse PG classificationNA
click here to return to the previous page