Gene Information
Gene NameDNAH7
OrganismHomo sapiens (Human)
Gene Length4024
Protein NamesDynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000118997 )
Evolutionary StageEukaryota
AlphaFoldDBNA
Gene CardDNAH7
Uniprot IDQ8WXX0
PfamPF12774; PF12780; PF12781; PF17857; PF18198; PF08393; PF17852; PF18199; PF03028; PF12777
In ASDno
Allosteric Predictionno (-1.124297259)
Ortholog in AnimalsAlpaca_ DNAH7 ( ortholog_one2one )
Dog_ DNAH7 ( ortholog_one2one )
GuineaPig_ DNAH7 ( ortholog_one2one )
Macaque_ DNAH7 ( ortholog_one2one )
Mouse_ Dnah7a ( ortholog_one2many )
Mouse_ Dnah7c ( ortholog_one2many )
Mouse_ Dnah7b ( ortholog_one2many )
Pig_ DNAH7 ( ortholog_one2one )
Rat_ Dnah7 ( ortholog_one2one )
Rabbit_ DNAH7 ( ortholog_one2one )
OhnologsDNAH8, DNAH10
ParalogsDNAH3, DNHD1, DNAH14, DNAH9, DYNC1H1, DNAH12, DNAH2, DNAH17, DYNC2H1, DNAH10, DNAH6, DNAH1, DNAH5, DNAH8, DNAH11
TissueNA
Tissue SpecificityDetected in brain, testis and trachea. Detected in bronchial cells (at protein level). {ECO:0000269|PubMed:11175280, ECO:0000269|PubMed:11877439}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6RZA  (EM  5.40A 
DBSNP rs1072599  rs2375643  rs17838596  rs16843720  rs10931715  rs2635718  rs10198893  rs6719500  rs168192  rs13415574  rs13034775  rs2375544  rs2889109  rs10184131  rs16841199  rs2293066  rs16841018  rs13411834  rs6708527 
Subcellular location [CC]Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:11877439}.
Mouse PG classificationNA
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