| Gene Information | |
|---|---|
| Gene Name | OSBP8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 950 |
| Protein Names | Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BXW6 |
| Gene Card | OSBPL1A |
| Uniprot ID | Q9BXW6 |
| Pfam | PF12796; PF13857; PF01237 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5ZM5 (X-ray 2.60A ) 5ZM6 (X-ray 2.70A ) 5ZM7 (X-ray 3.40A ) 6IYB (X-ray 2.09A ) 6TQS (X-ray 2.25A ) |
| DBSNP | rs35693789 |
| Subcellular location [CC] | Late endosome {ECO:0000269|PubMed:16176980, ECO:0000269|PubMed:29858488}. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes. |
| Mouse PG classification | NA |
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