| Gene Information | |
|---|---|
| Gene Name | OS9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 667 |
| Protein Names | Protein OS-9 (Amplified in osteosarcoma 9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000135506 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13438 |
| Gene Card | OS9 |
| Uniprot ID | Q13438 |
| Pfam | PF07915 |
| In ASD | no |
| Allosteric Prediction | no (-0.436539042) |
| Ortholog in Animals | Alpaca_ OS9 ( ortholog_one2one ) Dog_ OS9 ( ortholog_one2one ) GuineaPig_ OS9 ( ortholog_one2one ) Macaque_ OS9 ( ortholog_one2one ) Mouse_ Os9 ( ortholog_one2one ) Pig_ OS9 ( ortholog_one2one ) Rat_ Os9 ( ortholog_one2one ) Rabbit_ OS9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ERLEC1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Found as well in all tumor cell lines analyzed, amplified in sarcomas. Highly expressed in osteosarcoma SJSA-1 and rhabdomyosarcoma Rh30 cell lines. Isoform 2 is the major isoform detected in all cell types examined. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.059582(Rat);0.104278(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3AIH (X-ray 2.10A ) |
| DBSNP | rs141986192 rs1804598 rs34764811 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000269|PubMed:18264092, ECO:0000269|PubMed:18417469, ECO:0000269|PubMed:19084021}. |
| Mouse PG classification | NA |
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