| Gene Information | |
|---|---|
| Gene Name | GRWD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 446 |
| Protein Names | Glutamate-rich WD repeat-containing protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000105447 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BQ67 |
| Gene Card | GRWD1 |
| Uniprot ID | Q9BQ67 |
| Pfam | PF12265; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.404414999) |
| Ortholog in Animals | Alpaca_ GRWD1 ( ortholog_one2one ) Dog_ GRWD1 ( ortholog_one2one ) Macaque_ GRWD1 ( ortholog_one2one ) Mouse_ Grwd1 ( ortholog_one2one ) Pig_ GRWD1 ( ortholog_one2one ) Rat_ Grwd1 ( ortholog_one2one ) Rabbit_ GRWD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RBBP4, GEMIN5, WDR59, ERCC8, WDR77, RBBP7, WDR73, PEX7, WDR24 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002354(Rat);0.008333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2302951 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. Nucleus {ECO:0000269|PubMed:25990725}. Chromosome {ECO:0000269|PubMed:25990725}. Note=Present in the nucleus throughout interphase and is detached from chromatin at the onset of mitosis and rebinds at telophase when the pre-replication complexes (pre-RC) is formed (PubMed:25990725). {ECO:0000269|PubMed:25990725}. |
| Mouse PG classification | NA |
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