| Gene Information | |
|---|---|
| Gene Name | WDR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 606 |
| Protein Names | WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000071127 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75083 |
| Gene Card | WDR1 |
| Uniprot ID | O75083 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.039485218) |
| Ortholog in Animals | Alpaca_ WDR1 ( ortholog_one2one ) Dog_ WDR1 ( ortholog_one2one ) GuineaPig_ WDR1 ( ortholog_one2one ) Macaque_ WDR1 ( ortholog_one2one ) Mouse_ Wdr1 ( ortholog_one2one ) Pig_ WDR1 ( ortholog_one2one ) Rat_ Wdr1 ( ortholog_one2one ) Rabbit_ WDR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in peripheral blood mononuclear cells (at protein level). {ECO:0000269|PubMed:29751004}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.017143(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13441 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:27994071}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q5RKI0}. Cell projection, podosome {ECO:0000269|PubMed:22721921}. Cell junction {ECO:0000269|PubMed:25792565}. |
| Mouse PG classification | NA |
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