| Gene Information | |
|---|---|
| Gene Name | PRG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 225 |
| Protein Names | Proteoglycan 3 (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000156575 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9Y2Y8 |
| Gene Card | PRG3 |
| Uniprot ID | Q9Y2Y8 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | yes (0.12212736) |
| Ortholog in Animals | Alpaca_ PRG3 ( ortholog_one2one ) Dog_ PRG3 ( ortholog_one2one ) Macaque_ PRG3 ( ortholog_one2one ) Mouse_ Prg3 ( ortholog_one2one ) Rat_ Prg3 ( ortholog_one2one ) Rabbit_ PRG3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRG2 |
| Tissue | bone.marrow |
| Tissue Specificity | Expressed in bone marrow. Not detected in placenta. {ECO:0000269|PubMed:10318872}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs669661 rs540687 |
| Subcellular location [CC] | Cytoplasmic granule {ECO:0000269|PubMed:10318872}. Note=Localized to the eosinophil secondary granule. |
| Mouse PG classification | NA |
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