| Gene Information | |
|---|---|
| Gene Name | ORC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 301 |
| Protein Names | Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000085840 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y619 |
| Gene Card | SLC25A15 |
| Uniprot ID | Q9Y619 |
| Pfam | PF00153 |
| In ASD | no |
| Allosteric Prediction | no (-0.144849) |
| Ortholog in Animals | Alpaca_ ORC1 ( ortholog_one2one ) Dog_ ORC1 ( ortholog_one2one ) GuineaPig_ ORC1 ( ortholog_one2one ) Macaque_ ORC1 ( ortholog_one2one ) Mouse_ Orc1 ( ortholog_one2one ) Pig_ ORC1 ( ortholog_one2one ) Rat_ Orc1 ( ortholog_one2one ) Rabbit_ ORC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDC6 |
| Tissue | bone.marrow |
| Tissue Specificity | Highly expressed in liver, pancreas, testis, lung and small intestine. Lower levels are detected in spleen, kidney, brain and heart. {ECO:0000269|PubMed:12807890}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1208994024 rs104894430 rs121908533 rs1064793683 rs121908534 rs199894905 rs104894424 rs141028076 rs202247803 rs202247804 rs1417167600 rs17849654 rs121908535 rs202247808 rs104894431 rs202247809 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q12375}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:10369256}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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