| Gene Information | |
|---|---|
| Gene Name | TUBA4A |
| Organism | Homo sapiens (Human) |
| Gene Length | 448 |
| Protein Names | Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain) |
| Target Name | tubulin alpha-4a chain |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000127824 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P68366 |
| Gene Card | TUBA4A |
| Uniprot ID | P68366 |
| Pfam | PF00091; PF03953 |
| In ASD | no |
| Allosteric Prediction | yes (0.827963962) |
| Ortholog in Animals | Alpaca_ TUBA4A ( ortholog_one2one ) Dog_ TUBA4A ( ortholog_one2one ) GuineaPig_ TUBA4A ( ortholog_one2one ) Macaque_ TUBA4A ( ortholog_one2one ) Mouse_ Tuba4a ( ortholog_one2one ) Pig_ TUBA4A ( ortholog_one2one ) Rat_ Tuba4a ( ortholog_one2one ) Rabbit_ TUBA4A ( ortholog_one2one ) |
| Ohnologs | TUBA1B, TUBA1A, TUBA1C, TUBA3D |
| Paralogs | TUBB, TUBA4B, TUBA8, TUBB6, TUBB3, TUBAL3, TUBG2, TUBB8, TUBB8B, TUBE1, TUBB1, TUBB4B, TUBB4A, TUBA1B, TUBA1A, TUBA1C, TUBA3E, TUBA3C, TUBA3D, TUBD1, TUBG1, TUBB2A, TUBB2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);0.035(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs730880029 rs730880028 rs730880025 rs730880026 rs368743618 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. |
| Mouse PG classification | NA |
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